The Filmfare Best Actress Award is given by the Filmfare magazine as part of its annual Filmfare Awards South for Malayalam films.
The award was first given in 1992.
| Year | Winner | Film(s) |
|---|---|---|
| 2001 | Samyuktha Varma | Mazha |
| 2002 | Samyuktha Varma | Megamalhar |
| 2003 | ||
| 2004 | Meera Jasmine | Kasthoorimann |
| 2005 | Geethu Mohandas | Akale |
| 2006 | Meera Jasmine | Achuvinte Amma |
| 2007 | Padmapriya | Karuthapakshikal |
| 2008 | Meera Jasmine | Ore Kadal |
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