The IIFA Best Actress Award is chosen by the viewers and the winner is announced at the actual ceremony. The most wins are by Rani Mukerji, leading with three consecutive wins.
The winners are listed below:-
| Year | Actress | Film |
|---|---|---|
| 2000 | Aishwarya Rai | Hum Dil De Chuke Sanam |
| 2001 | Karisma Kapoor | Fiza |
| 2002 | Tabu | Chandni Bar |
| 2003 | Aishwarya Rai | Devdas |
| 2004 | Preity Zinta | Kal Ho Naa Ho |
| 2005 | Rani Mukerji | Hum Tum |
| 2006 | Rani Mukerji | Black |
| 2007 | Rani Mukerji | Kabhi Alvida Naa Kehna |
| 2008 | Kareena Kapoor | Jab We Met |
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